The “salmon DNA” treatment behind Korea’s glass-skin results is now at Serene Med Spa. PDRN tells damaged skin cells to repair, rehydrate and rebuild elasticity — the fix for crepey, dehydrated, tired-looking skin. $199 per treatment.
Book Your Consultation Text (304) 396-0295 Call (304) 520-0461
PDRN (polydeoxyribonucleotide) is a purified DNA extract that has been used in wound care and surgery for decades. In aesthetics it became famous through Korean skin boosters, where it is prized for turning thin, dry, crepey skin into plump, elastic, luminous skin without adding volume or freezing movement.
At Serene Med Spa in Barboursville we deliver PDRN with microneedling, which creates thousands of micro-channels so the serum reaches the dermis where it works. The treatment takes about an hour with numbing, leaves light pinkness for a day, and builds results over a series: better hydration first, then firmness and a smoother, brighter surface. It is our go-to for the neck, chest and under-eyes, where filler and strong lasers are poor fits, and it stacks well with exosomes for inflamed or post-laser skin.
Rebuilds elasticity in the neck, chest, hands and under-eye area.
Improves the skin’s own water-holding capacity rather than sitting on top of it.
A brighter, more reflective surface as repair and turnover increase.
Softens early lines by restoring the dermis rather than filling or relaxing.
Supports healing in scarred or sun-damaged skin over a series.
Speeds recovery after laser, peels or Morpheus8.
We assess hydration, elasticity, sun damage and your goals, and decide whether PDRN alone, PDRN with exosomes, or PDRN on top of a laser or Morpheus8 plan is right for you.
Numbing cream for 20–30 minutes, then microneedling with PDRN serum layered into the skin. About an hour start to finish.
Light pinkness for a day. Hydration and glow improve within one to two weeks; elasticity and texture build over two to three months.
A series of three, four weeks apart, is standard; maintenance every three to six months. Sunscreen daily, no actives for 48 hours.
PDRN is new to most of the region, and results depend on a real polynucleotide product delivered properly, not a “salmon DNA” serum from a facial menu. Our physician-led team uses a medical-grade PDRN, delivers it with controlled-depth microneedling, and can combine it with exosomes, PRP or PRF based on what your skin actually needs. Pricing is published and the consultation is complimentary.
Book a Consultation$199 / treatment
Face; neck, chest, hands or under-eyes quoted at consultation
$199 / treatment
Growth-factor signaling
$100
Stack with PDRN, laser or Morpheus8
$299 / treatment
Your own platelet-rich plasma · series of 3 $799
Complimentary
No commitment
All regenerative microneedling treatments are performed by our physician-led team. Prices are per treatment; a series of three spaced four to six weeks apart gives the best result. See the full price list.
Microneedling with PDRN is $199 per treatment at Serene Med Spa in Barboursville. A series of three gives the best result.
Polydeoxyribonucleotide is a mix of DNA fragments purified from salmon, chosen because salmon DNA is nearly identical to human DNA in structure and triggers no immune reaction. It has been used in European wound care since the 1990s.
Rejuran is a Korean brand of injectable polynucleotide that is not FDA-approved in the United States. We deliver PDRN topically with microneedling, which brings the same active into the skin without injection.
PDRN primarily repairs tissue and improves hydration and elasticity. Exosomes carry a broader set of growth factors and anti-inflammatory signals. For crepey, dry skin we start with PDRN; for dull, inflamed or post-laser skin we lean toward exosomes. Many patients alternate or combine them.
Hyaluronic acid boosters add water to the skin for a few months. PDRN teaches the skin to hold its own water and rebuild collagen, so results develop more slowly but last longer and improve texture, not just hydration.
Yes. These are the areas we use it most, because PDRN firms thin skin without the lumps or puffiness that filler can cause there.
Mild pinkness for about a day. Makeup the next day is fine.
Anyone with a fish allergy (ask us; purified PDRN contains no fish protein, but we screen), active skin infection, pregnancy or nursing, or a history of keloid scarring should talk with our physician first.
"Dr. Shweta Arora is skilled with fillers & Botox. She listens to your concerns and looks at your face to see what is needed! I look and feel 10 yrs younger after the first visit. She starts conservatively which is nice if it’s your first time. Love Serene Spa in Barboursville."
"Dr Arora is the best! So considerate and patient. Took the time to answer my many questions without trying to rush me out. Extremely thorough and knowledgeable. I recommend emphatically. He does not disappoint."
"Great service and great staff. Very helpful with any questions. I always leave feeling taken care of and looking my best."
★★★★★ Verified reviews from our patients on Google
Individual results may vary. Photos of our own patients, shared with consent.
Located just off I-64 in Barboursville, Serene Med Spa welcomes patients seeking PDRN salmon DNA skin booster treatments from across Cabell, Wayne, Lincoln and Putnam counties in West Virginia, Lawrence County, Ohio, and Boyd & Greenup counties in Kentucky — including the communities below.
Monthly payment plans through Cherry and CareCredit, with 0% APR options for qualified patients. Applying with Cherry doesn’t affect your credit score.
How Easy Pay works ›Book PDRN microneedling online or schedule a complimentary consultation with our Barboursville team.
Book Your VisitTell us what you’re interested in and our team will reach out to schedule your visit.
A member of our team will reach out within one business day. Prefer not to wait? Book online now or text (304) 396-0295 or call (304) 520-0461.
